If you wish to host multiple KnowWE-wiki domains on a single webserver here are the steps you will need to take:
Stop currently running KnowWE-Server.
Copy the KnoweWE directory from ${KnowWE.home}\webapps\ to the same location and rename it to <YourWikiName>
Update the wikicontent location (var.basedir) in WEB-INF/classes/jspwiki-custom.properties of the copy, see: d3web-KnowWE - change wikicontent location. In the same file set jspwiki.baseURL to the new address (e.g. http://localhost:8080/<YourWikiName>/) and give the wiki its own jspwiki.applicationName.
Access your newly created Wiki like this: http://localhost:8080/<YourWikiName>
Repeat 1. - 6. this a often as you like, but check the memory consumption of the web server.
(You my need to change JAVA_OPTS in your environment settings depending on your hardware capabilities to e.g.: